calcium sensing receptor การใช้

Strontium ranelate stimulates the calcium sensing receptors and leads to the differentiation of pre-osteoblast to osteoblast which increases the bone formation.
In lactation, it may regulate in conjunction with the calcium sensing receptor the mobilization and transfer of calcium to the milk, as well as placental transfer of calcium.
His laboratory identified a potassium excretion regulatory channel involved in Bartter's syndrome type II, two sodium chloride transporters, and a calcium-sensing receptor known as CaSR which led to the development of a new class of drugs that modulate calcium sensing receptor activity.
My essay is shaping up ok now, can someone read this and tell me if its correct :'PTH acts by binding to Calcium sensing receptors ( CaSR ) in the kidneys activating renal adenyl cyclase to increase intracellular concentrations of cyclic AMP which activates protein kinase A and C .'Although now I've got a bit stuck again, what would activating protein kinase A and C do?